Man United lost a third successive Cup semi final this season on Sunday night.
Having earlier been beaten in both the Carling and FA Cup semi finals, the Red Devils were dumped out of the Europa League at the last four by Sevilla.
They took an early lead through a Bruno Fernandes penalty inside 9 minutes but we’re pegged back on 26 minutes thanks to Suso.
Substitute Luke De Jong scored the winner on 78 minutes off a Jesus Navas cross to ensure Sevilla progress to the final.
The other Europa League semi final will be played on Monday between Inter Milan and Shakhtar Donestk.
In the Champions, PSG will take on RB Leipzig while Bayern Munich face Man City in the semis.
PSG came from a goal down to overcome a tricky Atalanta side 2-1 on Wednesday night.
Mario Pasalic gave the Italians a shock lead on 26 minutes but PSG scored twice in injury time through Maquinhos and Eric Maxim Choupo Mouting to seal a famous victory.
On Thursday, RB Leipzig scrapped to a 2-1 victory over the much-fancied Atletico Madrid.
After a goalless first half, Danny Olmo opened the scoring on 50 minutes for Leipzing before Joao Felix converted from the spot to level matters.
With the game headed to extra time, Tayler Adams won it for the Germans two minutes from the end.
On Friday, Bayern Munich humiliated Barcelona 8-2.
Thomas Muller and substitute Philip Coutinho each scored a brace while Robert Lewandowski, Joshua Kimmich, Serge Gnabry and Ivan Perisic each netted once for the Bavarians.
For Barcelona, they struck through a David Alaba own goal and Luis Suarez’s second half goal.
In the last semi final, Olympique Lyon upset the odds as they beat Man City 3-1.
Maxiwell Cornet gave Lyon a first half lead before Kevin De Bruyne equalized for City on 69 minutes. It then fell to substitute Mousa Dembele who scored twice in the last 11 minutes to ensure Lyon reach the last four.
The Champions League semis will see PSG face RB Leipzig on Tuesday while Bayern entertain Lyon the following day.